BDBM448319 GC-376::GC376

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCNC1=O)C(O)S([O-])(=O)=O

InChI Key InChIKey=BSPZFJDYQHDZNR-ASPXRTSYSA-M

Data  1 KI  24 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448319   

TargetCathepsin K(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  0.260nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  0.560nMAssay Description:FRET-based enzymatic assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed